Ultrasound-aided synthesis of gold-loaded boron-doped graphene quantum dots interface towards simultaneous electrochemical determination of guanine and adenine biomolecules

Simple item page
dc.contributor.authorKaimal, Reshma
dc.contributor.authorMansukhlal, Patel Nishant
dc.contributor.authorAljafari, Belqasem
dc.contributor.authorAnandan, Sambandam
dc.contributor.authorAshokkumar, Muthupandian
dc.date.accessioned2026-08-22T09:08:19Z
dc.date.available2026-08-22T09:08:19Z
dc.date.issued2022-01-19
dc.description.abstractTo acquire substantial electrochemical signals of guanine-GUA and adenine-ADE present in deoxyribonucleic acid-DNA, it is critical to investigate innovative electrode materials and their interfaces. In this study, gold-loaded boron-doped graphene quantum dots (Au@B-GQDs) interface was prepared via ultrasound-aided reduction method for monitoring GUA and ADE electrochemically. Transmission electron microscopy-TEM, Ultraviolet–Visible spectroscopy-UV–Vis, Raman spectroscopy, X-ray photoelectron spectroscopy-XPS, cyclic voltammetry-CV, and differential pulse voltammetry-DPV were used to examine the microstructure of the fabricated interface and demonstrate its electrochemical characteristics. The sensor was constructed by depositing the as-prepared Au@B-GQDs as a thin layer on a glassy carbon-GC electrode by the drop-casting method and carried out the electrochemical studies. The resulting sensor exhibited a good response with a wide linear range (GUA = 0.5–20 μM, ADE = 0.1–20 μM), a low detection limit-LOD (GUA = 1.71 μM, ADE = 1.84 μM), excellent sensitivity (GUA = 0.0820 µAµM−1, ADE = 0.1561 µAµM−1) and selectivity with common interferents results from biological matrixes. Furthermore, it seems to have prominent selectivity, reproducibility, repeatability, and long-lasting stability. The results demonstrate that the fabricated Au@B-GQDs/GC electrode is a simple and effective sensing platform for detecting GUA and ADE in neutral media at low potential as it exhibited prominent synergistic impact and outstanding electrocatalytic activity corresponding to individual AuNPs and B-GQDs modified electrodes. © 2022 The Author(s)
dc.identifier.issn1350-4177
dc.identifier.urihttps://doi.org/10.1016/j.ultsonch.2022.105921
dc.identifier.urihttp://nitt.ndl.gov.in/handle/123456789/222
dc.language.isoen
dc.publisherElsevier B.V
dc.relation.ispartofseriesUltrasonics Sonochemistry; Vol. 83/ Art. 105921
dc.titleUltrasound-aided synthesis of gold-loaded boron-doped graphene quantum dots interface towards simultaneous electrochemical determination of guanine and adenine biomolecules
dc.typeArticle
Files
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Ultrasound-aided synthesis of gold-loaded boron-doped graphene quantum dots interface towards simultaneous electrochemical determination of guanine and adenine biomolecules.pdf
Size:
11.89 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
373 B
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Journal Articles